IVF

IVF in Iran

More than 2,500 Iranian and foreign patients are going under IVF treatment in Iran each year. IVF treatment in Iran is on top of the Middle East regarding its skilled specialists and surgeons. Here are the best hospitals for IVF in Iran:

  • Royan Clinic
  • Ebne Sina Clinic

There is a significant difference between the cost of IVF in Iran and other countries. The most important factors for the low price of it in Iran are:

  • A large number of IVF hospitals in Iran
  • A large number of applicants for IVF in Iran

IVF cost in Iran varies depending on the surgery and the hospital. The average cost of IVF in Iran is

More than 24,000 fertility treatments are being performed each year in Iran. Experienced Iranian doctors with an excellent record are performing the operations. One of the most important factors in choosing a good surgeon for IVF in Iran is the doctor has done many IVF surgeries.

Many patients travel to Iran for an IVF. One of the reasons for this matter is Iranian specialists and surgeons who have high surgery success rates. 

  • low cost of IVF in Iran
  • low cost of accommodation in Iran
  • Well experienced doctors
  • The high number of IVF in Iran

Diagnostic and surgical centres accordance with today’s European standards are performing the highest quality operations in Iran. Another reason for IVF in Iran is its lower cost compared to other countries.

 About IVF

In vitro fertilization is a procedure in which fertilization takes place when an egg cell meets a sperm under laboratory conditions. Doctors put one or more egg cells in the uterus after some cell division phases. They put an eight-cell embryo on day 5 in the uterus so that the embryonic development process continues naturally. In this method, first, ovulation induction is done in women, and after receiving an appropriate amount of ovum, they will develop them in the lab. After ova maturation, they will be fertilized by sperm. After evaluating egg cell quality, they put one or more embryos in the mother’s uterus. 

  • Women with blocked fallopian tubes or women who suffer from pelvic organ adhesion or fallopian tube adhesion or injuries
  • Men and women suffering from genetic disorders
  • Women suffering from disorders of the ovulation process
  • Women suffering from premature ovarian failure
  • Men who have low sperm count or low sperm motility
  • Unexplained infertility

Sonography is required to examine the ovary and the uterusconditions on the second or third day of the mother’s period.

After sonography, a specialist prescribes medicine in order to stimulate ovulation.

Five to six sessions of sonography are required while using the medicine to examine ova reactions.

When follicles reach the appropriate size, HCG will be injected to make the patient ready for the egg collection process.

36 hours after the HCG injection, sample sperm will be collected from the father and then fertilization occurs in the lab.

The in vitro fertilization (IVF) process takes four to six weeks generally. Stages of this infertility treatment method are divided into the following five stages:

First stage: Ovulation induction medication is prescribed. This medication should be used between 8 to 14 days before the period begins. If the inducing medication is effective, the doctor allows the second stage.

Second stage: The doctor guides a needle through the vagina, and it suctions the eggs out of follicles. There is no need for general anesthesia in his stage. Only local anesthesia and numbness are performed. 8 to 15 eggs are drawn out in this stage. The patient should be fasting during this stage.

Third stage: A sample of a man’s sperm is collected for fertilization.

Fourth stage: The man’s sperm combines with the woman’s ovum. They are placed in a dish for fertilization. These eggs are directly under doctors’ and specialists’ supervision. After the fertilization and division’s success; the fertilized egg is called an embryo.

Fifth stage: It is the last stage of the IVF process, which takes 3 to 5 days to transfer the embryo to the uterus after the fertilized egg cell retrieval. There is no need for anesthesia in this stage, and they put the embryo into the woman’s uterus. This method is pain-free in most cases, and the patient is discharged after 1 to 2 hours.

There is no need for general anesthesia in this method. Only numbness and local anesthesia are performed.

21 days

A hormonal test will be taken from the patient to measure BHCG in the blood 10 to 12 days after the embryo transfer. The rise in this hormone is the first sign of pregnancy.

The patient will be discharged from the hospital 1 to 2 hours after the embryo transfer surgery, and she/he can go back to daily activities. It is recommended to avoid heavy activities 3 to 4 days after the surgery.

  • Abdomen pain
  • Nausea
  • Weakness and dizziness
  • Bleeding
  • A short anesthesia of the woman is necessary during the removal of the eggs from the ovary and in some cases during the transfer of the embryo.
  • In some cases where many follicles are observed during ultrasound, some liquid may gather in the lady’s abdomen, (ovarian hyperstimulation syndrome (OHSS)). The treatment varies depending on the volume of the liquid in the abdomen.
  • The number of eggs can’t be determined with ultrasound. The exact number of eggs will be announced to the patient after ovulation observation and counting under the IVF lab microscope.
  • The number of eggs retrieved during the retrieval operation may vary from the number of follicles observed during ultrasound.
  • In 2-3% of the cases, follicles observed during ultrasound may lack eggs, in which case no eggs will be obtained on the operation day.
  •  IVF will not be performed with premature or malformed eggs.
  • For IVF, a sperm sample of the spouse is required on the day of egg retrieval.
  • The exact number and the quality of the produced embryos will be announced to the patient on the third day after egg retrieval.
  • Usually, two embryos will be transferred inside the womb and the rest of the embryos will be frozen on narrow straws. Low-quality embryos which have no possibility of impregnation and returning from freeze, will be eliminated 3 to 5 days after egg retrieval.
  • Embryos may have low quality after returning from freezing and not be suitable to transfer to the womb. Upon agreement of the patient, this transfer will not be made and the embryos will be removed.
  • There is a probability of ovarian abscess after egg removal. This probability will be significantly higher in patients with pelvic endometriosis or ovarian endometrioma cysts.
  • The process of microinjection and using hormonal medicines, necessary for this process, have no effect on the Gender and fetal health in terms of chromosomal and genetic aspects
  • Gender and fetal health in terms of chromosomal and genetic aspects can only be determined by PGS and PGD (genetic and chromosomal tests on known damaged genes to determine fetal health). Without these tests, embryo transfer can be done according to appearance quality. It’s noteworthy that fetal health and gender can not be determined at all by looking at the embryo’s appearance.
  • In cases where PGD and PGS are done, fetal health can be reliably checked in the 16th week of pregnancy with an amniocentesis test. 
  • 41-43 percent for women under 35
  • 33-36 percent for women between 35 to 37
  • 23-27 percent for women between 38 to 40
  • 10-13 percent for women over 40
  • Ovary syndrome
  • Multiple births
  • Premature labour
  • Abortion
  • A short anesthesia of the woman is necessary during the removal of the eggs from the ovary and in some cases during the transfer of the embryo.
  • In some cases where many follicles are observed during ultrasound, some liquid may gather in the lady’s abdomen, (ovarian hyperstimulation syndrome (OHSS)). The treatment varies depending on the volume of the liquid in the abdomen.
  • The number of eggs can’t be determined with ultrasound. The exact number of eggs will be announced to the patient after ovulation observation and counting under the IVF lab microscope.
  • The number of eggs retrieved during the retrieval operation may vary from the number of follicles observed during ultrasound.
  • In 2-3% of the cases, follicles observed during ultrasound may lack eggs, in which case no eggs will be obtained on the operation day.
  •  IVF will not be performed with premature or malformed eggs.
  • For IVF, a sperm sample of the spouse is required on the day of egg retrieval.
  • The exact number and the quality of the produced embryos will be announced to the patient on the third day after egg retrieval.
  • Usually, two embryos will be transferred inside the womb and the rest of the embryos will be frozen on narrow straws. Low-quality embryos which have no possibility of impregnation and returning from freeze, will be eliminated 3 to 5 days after egg retrieval.
  • Embryos may have low quality after returning from freezing and not be suitable to transfer to the womb. Upon agreement of the patient, this transfer will not be made and the embryos will be removed.
  • There is a probability of ovarian abscess after egg removal. This probability will be significantly higher in patients with pelvic endometriosis or ovarian endometrioma cysts.
  • The process of microinjection and using hormonal medicines, necessary for this process, have no effect on the Gender and fetal health in terms of chromosomal and genetic aspects
  • Gender and fetal health in terms of chromosomal and genetic aspects can only be determined by PGS and PGD (genetic and chromosomal tests on known damaged genes to determine fetal health). Without these tests, embryo transfer can be done according to appearance quality. It’s noteworthy that fetal health and gender can not be determined at all by looking at the embryo’s appearance.
  • In cases where PGD and PGS are done, fetal health can be reliably checked in the 16th week of pregnancy with an amniocentesis test. 
  • 41-43 percent for women under 35
  • 33-36 percent for women between 35 to 37
  • 23-27 percent for women between 38 to 40
  • 10-13 percent for women over 40
  • Ovary syndrome
  • Multiple births
  • Premature labour
  • Abortion
Is IVF surgery painful?

IVF includes several parts. The hormone injection stage is pain-free. The egg retrieval stage is performed as an outpatient surgery with anesthesia for the pain. A painkiller medicine is injected, so there won’t be any discomfort. The embryo transfer stage is pain-free as well.

When can the process be repeated for the second time after an IVF failure?

This case depends on the person. The first reason for the postponement is a chance for the patient to return to her normal period cycle; which takes 2 to 3 monthly periods.

Is spotting after the egg retrieval process normal?

Yes. Because of the needle that has suctioned out the follicles through the uterus walls; some blood spots will be seen after the eggs are drawn out. You can see light blood spots 42 to 48 hours after the egg retrieval.

Is there a possibility of multiple births in IVF?

Yes. About 52 percent of the pregnancies are twins, and 2 to 3 percent of them are triplets.

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